Proinflammatory response of canine trophoblasts to Brucella canis infection
نویسندگان
چکیده
منابع مشابه
Proinflammatory response of canine trophoblasts to Brucella canis infection
Brucella canis infection is an important cause of late-term abortion in pregnant bitches. The pathophysiological mechanisms leading to B. canis-induced abortion are unknown, but heavily infected trophoblasts are consistently observed. As trophoblasts responses to other pathogens contribute to placental inflammation leading to abortion, the aim of the present study was to characterize the cytoki...
متن کاملCanine Brucellosis: Brucella canis
Canine brucellosis, caused by Brucella canis, is an important cause of reproductive failure, particularly in kennels. This organism causes abortions, stillbirths, epididymitis, orchitis and sperm abnormalities in dogs. Although dogs that have been spayed or neutered do not have reproductive signs, they occasionally develop other conditions such as ocular disease and discospondylitis. B. canis c...
متن کاملCanine Brucellosis Caused by Brucella Canis
Etiology and Epidemiology Canine brucellosis is caused by Brucella canis (B. canis), a rough, small, gram-negative, intracellular bacterium. Other Brucella species, i.e., B. abortus, B. suis, have occasionally caused canine infections but they are not discussed here. The canine brucella was first recognized in 1966 as a cause of abortions and reproductive failures and it has since been recogniz...
متن کاملHuman Brucella canis outbreak linked to infection in dogs.
The zoonotic risk of Brucella canis has been considered fairly high for persons who handle breeding dogs in kennels or are exposed to infected animals. Transmission to humans in other circumstances has been thought to be rare. We describe an uncommon outbreak of brucellosis caused by B. canis which, to the best of our knowledge, is the first reported in the literature. This outbreak involved si...
متن کاملVariability in the response of canine and human dendritic cells stimulated with Brucella canis
Brucella canis is a small intracellular Gram-negative bacterium whose primary host is the dog, but it also can cause mild human brucellosis. One of the main causes of an inefficient immune response against other species of Brucella is their interaction with dendritic cells (DCs), which affects antigen presentation and impairs the development of an effective Th1 immune response. This study analy...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLOS ONE
سال: 2017
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0186561